RNA, U2 small nuclear 8, pseudogene (RNU2-8P)

**RNA, U2 small nuclear 8, pseudogene (RNU2-8P)** is a human pseudogene that resembles genes encoding the U2 small nuclear RNA, a component of the spliceosome complex responsible for pre-mRNA splicing[1][4]. Unlike its functional counterparts, RNU2-8P is classified as a pseudogene, meaning it does not produce a functional RNA product and has no known biological function or disease association. Pseudogenes such as RNU2-8P typically arise from duplication or retrotransposition events and often contain sequence similarities to their functional parental genes but lack regulatory elements or contain disruptive mutations[4]. There is no evidence to support this as a therapeutic target, a biomarker, or a disease-causing locus. **Notes on correctness:** There is nothing technically misspelled in the name RNU2-8P, but the entity is a **pseudogene, not a protein, receptor, or functional RNA**, and it is not considered a drug target or a receptor. It should be annotated as a non-functional locus and not be included among actionable molecular targets such as enzymes or receptors[1][4].

Other names

RNU2-8PRNA, U2 small nuclear RNA 8, pseudogene