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RNA, U6 small nuclear 1133, pseudogene (RNU6-1133P)
- Target
- RNU6-1133P
- Molecular classification
- Pseudogene, Small nuclear RNA-derived sequence, Noncoding RNA
01
Overview
RNA, U6 small nuclear 1133, pseudogene (RNU6-1133P) is a human pseudogene derived from the U6 small nuclear RNA gene, located in the nuclear genome and classified as a processed pseudogene based on sequence analysis[3][5][7]. Pseudogenes are genomic DNA sequences similar to normal genes but generally considered nonfunctional due to mutations, truncations, or lack of necessary regulatory elements. The parental U6 small nuclear RNA is part of the spliceosome, a critical RNA–protein complex involved in pre-mRNA splicing. However, RNU6-1133P shows no evidence of transcriptional or translational activity and has not been implicated in disease, drug response, or normal cellular functions. Its existence reflects historical retrotransposition events rather than ongoing biological roles[4].
- Other names
- RNU6-186PGC06P031051many others
02
Mechanism of action
None known for drugs targeting this entity.
03
Biological functions
None established for RNU6-1133P specifically.U6 small nuclear RNA (parental gene) is normally involved in splicing as part of the spliceosome, but pseudogenes typically lack function[4].
04
Disease associations
None established for RNU6-1133P[3][5][7].Some pseudogenes can regulate the expression of their parental genes or act as decoys in miRNA pathways, but no evidence exists for this specific pseudogene[6].
05
Safety considerations
None known or anticipated, as pseudogenes are not generally targeted therapeutically.
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