RNA, U6 small nuclear 1135, pseudogene (RNU6-1135P)

RNU6-1135P is a processed pseudogene derived from the U6 small nuclear RNA gene, a pivotal non-coding RNA component of the spliceosome active in pre-mRNA splicing in eukaryotes[1][3]. Unlike functional U6 snRNA, pseudogenes such as RNU6-1135P result from retrotransposition events mediated by LINE-1 (L1) elements, and do not encode active RNA molecules or proteins nor participate in spliceosome assembly or cellular pathways[2][5]. Their sequences sometimes retain recognizable motifs or ends of U6 RNA but typically lack both intronic structure and functional secondary structure, often existing as nonfunctional genomic fragments[2][5]. These pseudogenes are prevalent in the vertebrate genome and are used by researchers to study retrotransposon activity and genome evolution, rather than serving as functional nucleic acids or drug targets[2][5][3]. If more information on functional U6 snRNA or other spliceosomal RNA targets is required, refer to research on U6 small nuclear RNA rather than its pseudogene variants, which have no direct biomedical utility[3][1].

Other names

RNU6-1135PRNA, U6 small nuclear 1135, pseudogeneU6 snRNA pseudogene

None (no mechanisms of drug action are applicable to this pseudogene)