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RNU6-1144P, or RNA, U6 small nuclear 1144, pseudogene, is a genomic sequence classified as a **pseudogene** of the U6 small nuclear RNA (snRNA) gene family[4][7]. Pseudogenes are copies of genes that have lost their ability to encode a functional RNA or protein product and do not have reported biological function or disease associations. RNU6-1144P shares sequence similarity with functional U6 snRNA genes, which are crucial for spliceosome assembly and pre-mRNA splicing, but as a pseudogene it is not transcribed into a functional RNA product[2][4][7].\nNo evidence exists for therapeutic targeting, interacting drugs, disease relevance, or biomarker utility for RNU6-1144P specifically. It is not considered an enzyme, transporter, receptor, or protein target, and its listing as a target is likely the result of misannotation. U6 snRNA pseudogenes are common in the human genome, reflecting ancestral retrotransposition and gene duplication events, but they do not contribute to canonical gene function[5].
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