Target intelligence / Profile preview

RNA, U6 small nuclear 1146, pseudogene (RNU6-1146P)

Target
RNU6-1146P
Molecular classification
Other (pseudogene, small nuclear RNA-derived)
01

Overview

RNU6-1146P refers to a *pseudogene* corresponding to a variant of U6 small nuclear RNA (snRNA). U6 snRNA is an essential component of the spliceosome, the molecular machinery responsible for excision of introns during pre-mRNA splicing in the nucleus of eukaryotes[1][3]. The RNU6-1146P nomenclature specifically refers to a nonfunctional, likely noncoding, pseudogene copy within the genome that does not code for a functional U6 snRNA molecule. Pseudogenes of U6 are common in vertebrate genomes and do not encode active RNAs or proteins; these duplicated or mutated genomic elements typically lack regulatory, catalytic, or cellular roles[1]. While some pseudogenes elsewhere in the genome can act as regulatory RNAs (such as antisense molecules or decoys), there is no evidence that RNU6-1146P possesses such regulatory function[2]. As a result, RNU6-1146P is not considered a receptor, enzyme, transporter, or therapeutic target and has no documented role in human disease biology or pharmacology. **Notes on correctness:** - This target is a *pseudogene* of U6 snRNA, not a functional coding gene, protein, or therapeutic target. - If you are searching for information on snRNP targets or active spliceosomal RNAs, you should instead refer to canonical U6 snRNA and its associated protein complexes, not this pseudogene. - Most databases and literature will not register RNU6-1146P as a valid biological or drug target, nor associate it with drug-interactions, biomarker roles, or disease relevance[1][3].

Other names
RNU6-1146PRNA, U6 small nuclear 1146 pseudogene
02

Biological functions

Other (no established function; typical pseudogene; may have minor regulatory RNA potential as seen for some pseudogenes)
03

Disease associations

Other (no disease role reported; pseudogene status)

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