RNA, U6 small nuclear 158, pseudogene (RNU6-158P)

RNU6-158P (RNA, U6 small nuclear 158, pseudogene) is a processed pseudogene derived from the U6 small nuclear RNA (snRNA) gene family. U6 snRNA itself is a highly conserved non-coding RNA critical for the spliceosome machinery, which carries out pre-mRNA splicing in eukaryotes[1][2]. However, RNU6-158P is a pseudogene, meaning it is a non-functional genetic relic that does not produce a functional RNA or protein product[3]. Pseudogenes like RNU6-158P are formed through genomic events such as retrotransposition or duplication but have lost their original biological function, often due to mutations or truncations[3]. U6 snRNA pseudogenes are numerous in vertebrate genomes, serving primarily as markers of genomic evolution and retrotransposition activity rather than active molecular roles[3]. This entry is not a receptor, enzyme, transporter, or otherwise considered a therapeutic target. No drugs, disease associations, biological functions, or mechanisms of action are attributed to this pseudogene. There are no known biomarker or safety concerns, as it is not an active molecule. Note: This entry is typically excluded from therapeutic or functional target lists and should not be considered a druggable or functional target.

Other names

RNU6-158PRNA, U6 snRNA pseudogene 158U6-158P