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RNA, U6 small nuclear 173, pseudogene (RNU6-173P) is a pseudogene related to the U6 small nuclear RNA family[5][6]. The canonical, functional U6 small nuclear RNA forms a central component of the spliceosome complex, directly participating in pre-mRNA splicing in eukaryotic cells by catalyzing intron removal[1][3]. However, RNU6-173P itself does not encode a functional U6 snRNA; it is classified as a pseudogene, meaning it is a non-functional, likely non-transcribed genetic element resulting from duplication or other genetic events that have incapacitated the locus[5][6]. RNU6-173P is not considered a biological or therapeutic target; there are no known drugs, disease associations, biomarkers, or relevant safety concerns[5][6]. Pseudogenes of U6 snRNA, such as RNU6-173P, are numerous in the human genome, reflecting the evolutionary importance and high copy number of functional U6 snRNA genes[3]. These pseudogenes are generally not transcribed and do not have a role in spliceosome function or any established physiological process[5][6].
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