RNA, U6 small nuclear 375, pseudogene (RNU6-375P)

**RNU6-375P** (RNA, U6 small nuclear 375, pseudogene) is a human pseudogene related to the U6 small nuclear RNA (snRNA) family[1][5][7]. U6 snRNA molecules are highly conserved non-coding RNAs essential for pre-mRNA splicing as a component of the spliceosome[5]. In contrast, RNU6-375P is classified as a pseudogene, meaning it does not encode a functional RNA[1][7]. Pseudogenes like RNU6-375P are typically non-functional genomic sequences arising from functional ancestors (in this case, U6 snRNA genes) through duplication or retrotransposition events[7]. These U6 pseudogenes are common in the human genome and are markers of retrotransposition but are not known to have an active biological or disease-related function, nor are they considered therapeutic targets, biomarkers, or subject to drug interactions[1][7].\n**Note:** This entry is often returned in gene/protein databases but does not correspond to a protein, enzyme, receptor, transporter, or actionable therapeutic molecule. There is nothing inherently "wrong" with its naming or identification, but it is not considered a druggable or clinically relevant target and should not be confused with functional U6 snRNA molecules[1][5][7].

Other names

RNU6-375PRNA, U6 snRNA pseudogene 375