RNA, U6 small nuclear 384, pseudogene (RNU6-384P)

**RNA, U6 small nuclear 384, pseudogene (RNU6-384P)** is a human pseudogene related to U6 small nuclear RNA (snRNA) family. U6 snRNA itself is a highly conserved, non-coding RNA that is a core component of the major spliceosome complex involved in pre-mRNA splicing, where it plays a critical structural and catalytic role[1][2]. However, *RNU6-384P* is one of many genomic loci annotated as *pseudogenes* for U6 snRNA, found throughout mammalian genomes, including in humans[2][3]. Pseudogenes, by definition, are genomic DNA sequences similar to known genes but are non-functional due to mutations or truncations that prevent normal expression or function[3]. There is no evidence that RNU6-384P is transcribed or functions as a protein or regulatory RNA. There is also no evidence in the scientific literature or clinical resources that this pseudogene serves as a therapeutic target, a disease biomarker, or is associated with a drug mechanism of action. Its "pseudogene" status means it should not be considered a target for therapeutic intervention, and it has no established physiological, pathological, or therapeutic relevance. If the intent was to refer to U6 small nuclear RNA (snRNA) itself, that is a distinct, functional molecule and a core part of the RNA splicing apparatus[1][2]; the pseudogene is non-functional and not a biologically relevant target.

Other names

RNU6-384PU6 small nuclear RNA pseudogene 384