RNA, U6 small nuclear 436, pseudogene (RNU6-436P)

RNA, U6 small nuclear 436, pseudogene (RNU6-436P) is a non-functional genomic sequence that resembles the functional U6 small nuclear RNA gene but does not produce a mature, active RNA product[5]. U6 snRNA (the functional parent) is a crucial component of the spliceosome, the complex responsible for removing introns from pre-mRNA during RNA splicing in eukaryotic cells[1][3]. U6 snRNA is highly conserved and essential for cell viability due to its role in forming the spliceosomal catalytic core[3]. However, the RNU6-436P pseudogene itself is a genomic relic that likely arose through duplication or retrotransposition events and does not encode a functional transcript or protein[5]. Pseudogenes like RNU6-436P can sometimes have regulatory roles, but there is no evidence for such a role in this case[5]. This gene is not considered a drug target, biomarker, or receptor; its inclusion as a target is incorrect.

Other names

RNU6-436PU6 snRNA pseudogene 436RNA, U6 small nuclear 436, pseudogene

None as a pseudogene