RNA, U6 small nuclear 588, pseudogene (RNU6-588P)

RNA, U6 small nuclear 588, pseudogene (RNU6-588P) is a pseudogene found in the human genome, identified by the gene symbol RNU6-588P[1][7]. Pseudogenes such as this are non-functional sequences that resemble functional genes—in this case, U6 small nuclear RNAs, which are essential for pre-mRNA splicing as components of the spliceosome[8]. Unlike functional U6 snRNA, RNU6-588P contains sequence homology to the authentic gene but harbors mutations or deletions that prevent it from acting as a component of the spliceosome, and it does not produce a functional RNA product[6][1]. There is no evidence that RNU6-588P functions as a protein-coding gene, as a receptor, enzyme, transporter, or other traditional drug target class. Although some pseudogenes are known to be transcribed and may have regulatory roles, there are currently no data supporting a biological or disease-modifying role for RNU6-588P itself[1][3][7].

Other names

RNU6-588P

Not applicable; not a pharmacologically actionable entity