RNA, U6 small nuclear 780, pseudogene (RNU6-780P)

RNU6-780P, also known as RNA, U6 small nuclear 780, pseudogene, is a pseudogene annotated in the human genome (Ensembl ID ENSG00000212332, HGNC:47743) and classified as a small nuclear RNA pseudogene located on chromosome 10[1][3][5][7]. Pseudogenes like RNU6-780P are typically derived from functional genes but acquire mutations that prevent their normal function, often lacking the ability to encode proteins or produce functional RNA[4]. Some pseudogenes can be transcribed and may exert regulatory functions at the RNA level, for example by acting as competing endogenous RNAs or generating small interfering RNAs, but there is currently no evidence or annotation suggesting that RNU6-780P has such functions[4]. It is not considered a therapeutic target, and there are no known drugs, disease associations, or biomarkers directly linked to this pseudogene. The parent U6 small nuclear RNAs (not the pseudogene) are key components of the spliceosome, essential for pre-mRNA splicing, but the pseudogene form is presumed to lack such activity[9]. According to gene resources, RNU6-780P is one of many U6 snRNA pseudogenes, with no current clinical or biological relevance assigned to it[1][3][5][7].

Other names

RNU6-780PRNA, U6 small nuclear 780, pseudogene