RNA, U6 small nuclear 932, pseudogene (RNU6-932P)

RNU6-932P, formally named "RNA, U6 small nuclear 932, pseudogene," is a human genomic locus classified as a **pseudogene** of U6 small nuclear RNA (snRNA)[7][8]. The canonical, functional U6 snRNA is a core, highly conserved non-coding RNA component of the spliceosome, essential for splicing of pre-mRNA in eukaryotic nuclei[1][5]. However, RNU6-932P is a **processed pseudogene**—a DNA sequence that derives from retrotransposition of functional U6 snRNA transcripts but does not produce a functional snRNA, due to lack of expression, necessary sequence elements, or regulatory features[2][7][8]. Pseudogenes of U6 snRNA, like RNU6-932P, are frequently found in the human genome and are formed by **L1 retrotransposition** of small nuclear RNA transcripts, often leaving truncated, nonfunctional genetic relics[2]. These pseudogenes do not encode proteins and typically have no biological function nor clinical relevance; they are not considered valid drug targets, biomarkers, or therapeutic receptors[2][7]. - **Note:** - RNU6-932P is not a protein, receptor, enzyme, transporter, or otherwise characterized as a therapeutic or druggable target. - The name is correct, but the entity is not a relevant molecular target; its classification as a pseudogene means it has no direct biological activity nor disease association. - There are no known drugs, disease associations, biomarkers, or safety concerns related to this pseudogene. Summary: RNU6-932P is a processed pseudogene copy of the highly conserved U6 snRNA gene, arising through retrotransposition and lacking functional or clinical significance[2][7][8]. It should not be considered a therapeutic target.

Other names

RNU6-932PRNA, U6 snRNA pseudogeneU6 snRNA pseudogene