RNA, U6 small nuclear 94, pseudogene (RNU6-94P)

RNA, U6 small nuclear 94, pseudogene (RNU6-94P) is classified as a **pseudogene** of the U6 small nuclear RNA (snRNA), specifically the 94th documented copy in the human genome[4][6]. U6 snRNA is a highly conserved, noncoding RNA that is a central component of the spliceosome—the macromolecular complex responsible for removing introns from pre-mRNA in eukaryotic cells[1][5]. However, as a **pseudogene**, RNU6-94P does not produce a functional RNA or protein product and lacks intrinsic biological or therapeutic activity[4]. Pseudogenes such as RNU6-94P are generally regarded as genomic relics generated by retrotransposition events—often involving LINE-1 retrotransposons—that integrate RNA-derived sequences back into the genome[3][7]. These copies are typically transcriptionally inactive, do not contribute to spliceosome function, and have no established roles in disease or therapy. They may, however, serve as genomic markers for studying retrotransposon dynamics and genome evolution[7].

Other names

RNU6-94PRNA, U6 Small Nuclear 94, Pseudogene