RNA, U6 small nuclear 966, pseudogene (RNU6-966P)

RNA, U6 small nuclear 966, pseudogene (RNU6-966P) is classified as a pseudogene related to the U6 small nuclear RNA (snRNA) gene family[2][8][7]. U6 snRNA is an essential component of the spliceosome, participating in the catalysis of pre-mRNA splicing in eukaryotic cells[1][3][5]. However, pseudogenes such as RNU6-966P are generally non-functional genomic sequences that resemble functional genes but do not produce active RNA or protein products; they arise through gene duplication or retrotransposition events[2][7]. No evidence supports any functional role for RNU6-966P in molecular biology or disease, nor is it considered a therapeutic or diagnostic target[2][8][6]. RNU6-966P is used primarily as a genomic marker and is studied for evolutionary and structural genomic insight into the U6 gene family, but it does not participate in biological processes or disease and is not targeted by drugs[2][8][7]. Its sequence is highly homologous to functional U6 snRNA genes, containing structural elements of the U6 sequence but with mutations or truncations that prevent function[7]. Note: "RNU6-966P" is a pseudogene and not a protein or RNA with an established therapeutic, biomarker, or biological target role; requests for target, disease, or drug-related information should refer to the functional U6 snRNA, not to its pseudogenes[2][8][7][6].

Other names

RNU6-966PRNA, U6 snRNA pseudogeneU6 pseudogene