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RNA binding motif protein 3 pseudogene (ENSG00000236741) is a non-functional genomic sequence that arose from the duplication or retrotransposition of the RBM3 gene and subsequently acquired mutations preventing it from coding for a functional protein. Pseudogenes such as this one are generally considered molecular fossils, though in rare cases, some may regulate their parent gene via RNA-based mechanisms, but this has not been established for this particular pseudogene. It is not considered a therapeutic target, is not referenced as a biomarker, and has no direct role in disease or drug interactions. Caution is required to avoid confusing this pseudogene with the protein-coding RBM3 gene, which does have biological and clinical relevance.
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