Target intelligence / Profile preview

RNA binding motif protein 45 pseudogene (RBM45 pseudogene)

Target
RBM45 pseudogene
Molecular classification
Pseudogene, Other
01

Overview

The RNA binding motif protein 45 pseudogene (ENSG00000254255) is a nonfunctional genomic sequence, homologous to the protein-coding gene RBM45, which belongs to the RNA recognition motif (RRM) family of RNA-binding proteins. While the functional RBM45 gene is involved in RNA processing and has links to neural development and neurodegenerative disease, the pseudogene lacks the ability to produce a functional protein and does not participate in canonical biological functions or serve as a therapeutic target. Pseudogenes such as this may sometimes play minor roles as genomic elements, but there is no evidence to support a druggable or biological role for ENSG00000254255 itself.

Other names
RBM45PRNA Binding Motif Protein 45, Pseudogene
02

Mechanism of action

None (pseudogene is not targeted by drugs)

03

Biological functions

Most pseudogenes have no functional protein product and typically do not directly contribute to biological processes.Possible regulatory DNA element effects in rare cases (unproven for this specific pseudogene).
04

Disease associations

None established for ENSG00000254255 itself.The functional RBM45 gene is associated with neurodegenerative disorders such as amyotrophic lateral sclerosis and Alzheimer's disease, but the pseudogene is not directly implicated.

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