Target intelligence / Profile preview

RNA-binding motif single-stranded-interacting protein 1 (RBMS1)

Target
RBMS1
Molecular classification
Single-stranded DNA-binding protein, RNA-binding protein, DNA-binding protein
01

Overview

RNA-binding motif single-stranded-interacting protein 1 (RBMS1) is a protein encoded by the RBMS1 gene in humans. It belongs to a family of proteins characterized by the presence of ribonucleoprotein consensus sequences (RNP-CS) required for binding single-stranded DNA and RNA. RBMS1 plays roles in DNA replication, gene transcription, cell cycle progression, and apoptosis. It can specifically bind single-stranded DNA motifs and is known to interact with regulatory regions upstream of the MYC oncogene, thus influencing important cellular processes and having potential implications in cancer biology. Multiple isoforms are produced through alternative splicing, and several aliases for RBMS1 exist due to its identification in various functional contexts.

Other names
C2orf12MSSPMSSP1SCR2MSSP-1MSSP-2MSSP-3YC1HCC-4DKFZp564H0764Single-stranded DNA-binding protein MSSP-1Suppressor of CDC2 with RNA-binding motif 2Suppressor of cdc 2 (cdc13) with RNA binding motif 2c-myc gene single strand binding protein 2cervical cancer oncogene 4
02

Biological functions

DNA replicationGene transcriptionCell cycle progressionApoptosisRNA bindingNucleic acid binding
03

Disease associations

Cancer (implicated via interaction with MYC, oncogene regulation)Primary biliary cirrhosisGlomerulonephritis

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