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Target intelligence / Profile preview
RNA-binding protein with multiple splicing 2 (RBPMS2)
- Target
- RBPMS2
- Molecular classification
- Other (RNA-binding protein)
01
Overview
RNA-binding protein with multiple splicing 2 (RBPMS2) is an RNA recognition motif-containing protein that regulates the early development and plasticity of smooth muscle cells, especially within the gastrointestinal system. It is involved in the control of cell differentiation and proliferation, and has been observed to be up-regulated in gastrointestinal stromal tumors[1][3][4]. There is no evidence it functions as a classical therapeutic target such as a receptor, enzyme, or transporter[1][3][4].
- Other names
- RNA binding protein, mRNA processing factor 2RNA binding protein with multiple splicing 2RBPMS2
02
Biological functions
Regulation of smooth muscle cell differentiationRegulation of smooth muscle cell proliferationmRNA processing
03
Disease associations
Cancer (notably up-regulated in gastrointestinal stromal tumors)Other
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