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RNA Polymerase (RNAP)
- Target
- RNAP
- Molecular classification
- Enzyme
01
Overview
RNA polymerase is a multi-subunit enzyme responsible for synthesizing RNA from a DNA template through the process of transcription. It plays a central role in gene expression by creating complementary RNA strands (including mRNA, rRNA, and tRNA) from DNA templates.
- Other names
- RNA polymerase IRNA polymerase IIRNA polymerase IIIDNA-dependent RNA polymerase
02
Mechanism of action
Inhibition of RNA synthesis
03
Biological functions
TranscriptionGene expressionRNA synthesis
04
Disease associations
CancerInfectionOther
05
Safety considerations
Cellular dysfunctionCell death
06
Interacting drugs
Antibiotics (targeting bacterial RNAPs)
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