RNA polymerase II subunit C pseudogene 1 (POLR2CP1)

RNA polymerase II subunit C pseudogene 1 (POLR2CP1) is a non-coding genetic locus on human chromosome 21, related to the POLR2C gene, which encodes the third-largest subunit of RNA polymerase II[5]. Unlike its functional parent (POLR2C), POLR2CP1 is a pseudogene: it does not encode a functional protein, has no established biological or therapeutic role, and is not considered a pharmacological target[1][5][7]. The parent protein, POLR2C, is a key component of the multi-subunit RNA polymerase II complex, which is essential for messenger RNA synthesis and eukaryotic transcription, but POLR2CP1 itself is non-functional[1][5][7]. For therapeutic or mechanistic information, one should refer instead to genes encoding functional RNA polymerase II subunits (such as POLR2C, POLR2A, etc.)[1][7].