RNA polymerase III subunit D pseudogene 1 (POLR3DP1)

POLR3DP1 is a processed pseudogene corresponding to the gene encoding subunit D (RPC4) of RNA polymerase III[5][4][6]. While its parent gene plays a critical role as part of a multi-subunit enzyme complex responsible for the synthesis of small RNAs such as tRNAs and 5S rRNA, the pseudogene POLR3DP1 itself does not code for a functional protein and is not implicated in biological processes, diseases, or therapeutic applications. It is distinct from the functional gene POLR3D (protein-coding), which is essential for transcription initiation by RNA polymerase III[7][1]. If searching for clinically or biologically important targets, the functional gene—RNA polymerase III subunit D (POLR3D)—and not the POLR3DP1 pseudogene should be considered.

Other names

Polymerase (RNA) III (DNA directed) polypeptide D, 44kDa pseudogene 1RNA polymerase III subunit D pseudogene 1POLR3DP1