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Target intelligence / Profile preview
RNA pseudouridylate synthase domain-containing protein 2 (RPUSD2)
- Target
- RPUSD2
- Molecular classification
- Enzyme
01
Overview
RNA pseudouridylate synthase domain-containing protein 2 (RPUSD2) is an enzyme that modifies RNAs by catalyzing the isomerization of uridine to pseudouridine in target mRNAs and non-coding RNAs, a process called pseudouridylation[6][2][5]. This post-transcriptional modification alters RNA structure and can impact RNA stability, processing, and function, but there is no clear evidence directly linking RPUSD2 to a specific disease or describing it as a therapeutic drug target[6][2].
- Other names
- Pseudouridylate synthase RPUSD2C15orf19C18B11FLJ31409PUS9RNA pseudouridine synthase domain containing 2C18B11 homolog
02
Biological functions
mRNA pseudouridine synthesisPseudouridine synthase activityRNA modification
03
Disease associations
Other
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