RNASEK-C17orf49 readthrough RNA (RNASEK-C17orf49)

RNASEK-C17orf49 readthrough is a naturally occurring non-coding RNA formed by the read-through transcription event between the adjacent RNASEK and C17orf49 genes on chromosome 17. This locus produces a transcript that is believed to be subject to nonsense-mediated mRNA decay and is therefore unlikely to encode a functional protein. Gene Ontology annotations related to this locus include possible chromatin binding. Because it is not protein-coding and does not encode a functional protein, it is not considered a typical therapeutic target such as a receptor, enzyme, transporter, or transcription factor[1][2][7]. Key details supporting these classifications: - The read-through transcript is categorized as a candidate for nonsense-mediated decay and does not produce a protein product[1][2][7]. - Descriptions in major genetic databases consistently refer to it as non-coding RNA rather than a protein or druggable target[1][2][7]. - While synonyms such as "BAP18," "C17orf49," and "BPTF-associated protein of 18 kDa" can refer to proteins, those are separate, protein-coding genes, not the readthrough transcript[1][5]. - No known drugs, disease associations, or established molecular functions exist for this RNA readthrough itself[1][2][7]. If your intent was to reference one of the protein products (for example, BAP18 encoded by C17orf49), that is a separate entity with distinct molecular and therapeutic relevance. The RNASEK-C17orf49 readthrough itself has no established role as a therapeutic target.

Other names

BAP18C17orf49BPTF-associated protein of 18 kDaChromatin complexes subunit BAP18RNASEK-C17orf49 readthrough (non-protein coding)