Target intelligence / Profile preview

RNF13 pseudogene 1 (RNF13P1)

Target
RNF13P1
Molecular classification
Other (pseudogene)
01

Overview

RNF13 pseudogene 1 (RNF13P1) refers to a pseudogene that is related to the RNF13 gene, which encodes a RING finger domain E3 ubiquitin-protein ligase involved in protein-protein interactions and regulation of cell proliferation and apoptosis. However, pseudogenes are generally non-functional genomic sequences resembling functional genes but lacking protein-coding capability. There is no evidence that RNF13P1 encodes a functional protein or acts as a therapeutic target. As such, it is not considered a druggable or disease-related target—unlike the protein-coding RNF13 gene itself. Information about RNF13 focuses on its protein-coding role (as a functional E3 ligase) and not on related pseudogenes. GeneCards and NCBI both note the existence of a pseudogene associated with RNF13 "also located on chromosome 3", but provide no further information, aliases, or known function for RNF13P1. No drug, disease role, or biological function is associated with RNF13 pseudogene 1 in the literature or authoritative genetic databases. Entries about RNF13P1 point to a likely incorrect use if intended as a target; the actual "target" is the protein-coding gene RNF13, not its pseudogene. In summary: RNF13P1 is a pseudogene, not a canonical therapeutic target, lacks functional annotation, does not have reported disease or drug associations, and referencing it as a target is likely mistaken or incorrect in the context of drug discovery or biology.

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