RNF185 antisense RNA 1 (RNF185-AS1)

RNF185 antisense RNA 1 (RNF185-AS1) is a long non-coding RNA (lncRNA) transcribed antisense to the RNF185 gene. As a non-coding transcript, RNF185-AS1 does not encode a protein but may play a regulatory role in gene expression. Recent research has shown that RNF185-AS1 is upregulated in papillary thyroid carcinoma and its increased expression promotes proliferation, migration, and invasion of cancer cells, suggesting it may contribute to tumor progression[4]. However, there are no approved drugs, biomarkers, or established therapeutic interventions directly targeting RNF185-AS1. Its activities are most likely exerted through modulating expression of target genes—either that of the sense RNF185 gene or others—in a manner typical of lncRNA-mediated regulation. Note: - The search results primarily detail RNF185 (the protein-coding E3 ubiquitin ligase; a classical therapeutic target) and not RNF185-AS1 (the lncRNA in question), except for one specific mention in cancer context[4]. - If the intention was to retrieve information on RNF185 (the protein-coding gene or its product), further clarification would yield a different answer with expanded therapeutic relevance.

Other names

RNF185-AS1lncRNA RNF185-AS1RNF185 antisense non-coding RNA 1