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RP11-832A4.7 (None established; sometimes abbreviated as RP11-832A4.7)
- Target
- None established; sometimes abbreviated as RP11-832A4.7
- Molecular classification
- Long non-coding RNA (lncRNA)
01
Overview
RP11-832A4.7 (ENSG00000280032) is a long non-coding RNA gene with regulatory roles in gene expression. It can act as an enhancer, recruit transcription factors, and interact with splicing factors, impacting the regulation of neighboring or target protein-coding genes. Differential expression of this lncRNA has been observed between tumor and normal tissues, with possible involvement in cancer biology, particularly prostate and lung cancers. However, there are no established direct therapeutic interventions targeting this lncRNA, nor is it classified as a canonical druggable target.
- Other names
- RP11-832A4.7
02
Mechanism of action
Not applicable; no drug mechanisms described for this molecule.
03
Biological functions
Regulation of gene expression as an enhancer lncRNARecruitment of transcription factorsModulation of alternative splicing by interacting with splicing factors
04
Disease associations
Expression changes observed in cancer types (downregulated in prostate adenocarcinoma; upregulated in lung squamous cell carcinoma)Correlation noted with cancer stage, especially prostate cancer
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