RPH3AL antisense RNA 2 (RPH3AL-AS2)

RPH3AL antisense RNA 2 (RPH3AL-AS2) is a long noncoding RNA (lncRNA) transcribed antisense to the RPH3AL gene on chromosome 17. As an antisense RNA, RPH3AL-AS2 is presumed to potentially regulate the expression of the RPH3AL gene—which encodes rabphilin 3A-like (without C2 domains), a protein involved in exocytosis and considered a tumor suppressor—but no direct biological, disease, or drug targeting role has been described for RPH3AL-AS2 itself in the available literature. There are currently no known aliases, disease associations, drug interactions, or clinical biomarker roles specifically ascribed to RPH3AL-AS2, and it is not established as a therapeutic target. Key interpretation notes: - Is this considered a therapeutic target? There is no evidence that RPH3AL-AS2 itself serves as a therapeutic target, receptor, enzyme, or clinically druggable entity. - Is there something wrong with this target? Yes: while RPH3AL-AS2 is a valid antisense ncRNA, it does not meet criteria for a druggable target as typically defined (receptor, enzyme, transporter, etc.), and essentially no functional or disease-specific information is available. The main target of interest in cancer or biology is its sense gene, RPH3AL (rabphilin 3A-like), a protein-coding tumor suppressor gene. - Alternative spellings/misunderstandings: RPH3AL-AS2 is not a receptor or a protein, and is unlikely to be the intended biological target for drug discovery. If drug discovery or pathway information is required, users should focus on the sense gene RPH3AL (Rabphilin 3A-like) and not on its antisense RNA transcript RPH3AL-AS2.

Other names

RPH3AL-AS2RPH3AL antisense RNA 2

Not applicable: no known drugs targeting this lncRNA