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Target intelligence / Profile preview
RPS6KA2 antisense RNA 1 (RPS6KA2-AS1)
- Target
- RPS6KA2-AS1
- Molecular classification
- Other (Long non-coding RNA)
01
Overview
RPS6KA2 antisense RNA 1 (RPS6KA2-AS1) is a long non-coding RNA (lncRNA) identified as antisense to the RPS6KA2 gene locus. Its precise function remains uncharacterized, but as with many antisense lncRNAs, it may have a regulatory role over its sense transcript or participate in epigenetic modulation. RPS6KA2-AS1 has been described as part of multi-lncRNA prognostic signatures in head and neck cancer and ovarian cancer in recent transcriptomic studies[2][4]. There is no current evidence that RPS6KA2-AS1 encodes a protein or acts as a direct therapeutic target such as a receptor, enzyme, transporter, or transcription factor.
- Other names
- RPS6KA2-AS1RPS6KA2 antisense RNA 1
02
Biological functions
Possible regulation of gene expression; no direct functional characterization found
03
Disease associations
Cancer (prognostic/predictive lncRNA in head and neck cancer and possibly ovarian cancer as part of multi-lncRNA gene signatures)
04
Biomarkers
Component of multi-lncRNA prognostic signatures in some cancers (head and neck, ovarian)
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