RSL1D1 divergent transcript (RSL1D1-DT)

The RSL1D1 divergent transcript (RSL1D1-DT) is an annotated non-coding RNA gene located near the protein-coding RSL1D1 gene. Divergent transcripts typically originate from the opposite strand adjacent to a coding gene and may play regulatory or structural roles in chromatin organization, transcriptional regulation, or RNA metabolism. There is currently no evidence that RSL1D1-DT encodes a functional protein, serves as a direct therapeutic target, or is associated with drug interaction, biomarker utility, or explicit safety considerations[4]. Most available functional and disease-related information instead pertains to the protein-coding RSL1D1 gene, not the divergent transcript. If your interest is in the RSL1D1 protein, refer to "Ribosomal L1 domain-containing protein 1" (RSL1D1), a regulator of cellular senescence, apoptosis, and cancer cell proliferation[1][2][3][5][6][8]. The entry for "RSL1D1-DT" is *not* a classical drug or therapeutic target—it's a genomic non-coding RNA locus annotation, and almost all relevant research and biological function discussion is about the protein-coding gene RSL1D1, not its non-coding divergent transcript[4].