Target intelligence / Profile preview

RSPH1 divergent transcript (RSPH1-DT)

Target
RSPH1-DT
Molecular classification
Other (Long non-coding RNA)
01

Overview

RSPH1-DT encodes a long non-coding RNA, distinct from the protein-coding gene RSPH1 (radial spoke head component 1). RSPH1-DT has no established function as a drug target or biomarker. The gene's transcript is annotated in databases, but no known protein, disease-role, or drug interactions have been described. Caution is warranted when searching for therapeutic relevance, as much literature confounds RSPH1-DT with RSPH1, which is implicated in ciliary function and disease but is a structurally and functionally distinct protein-coding gene[5][6]. If you seek information about the disease-relevant target, use “Radial spoke head component 1 (RSPH1)” rather than “RSPH1-DT.”

Other names
RSPH1-DTRSPH1 divergent transcript
02

Mechanism of action

None known

03

Biological functions

Other (lncRNAs may regulate gene expression but specific role for RSPH1-DT is uncharacterized)
04

Disease associations

None known for RSPH1-DT; RSPH1 (not RSPH1-DT) is associated with ciliary dysfunction and primary ciliary dyskinesia[1][2][4][5]
05

Safety considerations

None known
06

Interacting drugs

None known
07

Biomarkers

None known

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