Target intelligence / Profile preview

RWD domain-containing protein 4 (RWDD4)

Target
RWDD4
Molecular classification
Other
01

Overview

RWD domain-containing protein 4 (RWDD4) is a protein encoded in humans by the RWDD4 gene, with additional aliases including FAM28A and RWDD4A. It is a member of the RWD domain protein family, which are recognized for roles in protein-protein interactions. The specific function of RWDD4 is not clearly defined, and there is a lack of strong evidence connecting it to defined signaling pathways, enzyme activities, or transporter/receptor functions[9][12]. RWDD4 is a protein-coding gene with broad but low tissue specificity and poorly characterized biological roles. The gene is listed in some databases as being associated with calvarial doughnut lesions with bone fragility, but no definitive disease associations or relevance as a therapeutic target have been established[5][9]. As of now, no known drugs or mechanisms of action target RWDD4, and there are no established uses as a biomarker or known safety concerns in the therapeutic context.

Other names
FAM28ARWDD4AMGC10198Protein FAM28ARWD domain-containing protein 4Afamily with sequence similarity 28 member A
02

Biological functions

Unknownpossible participation in protein-protein interactionslimited evidence for regulatory functions
03

Disease associations

Other (an association with Calvarial doughnut lesions with bone fragility has been reported, but not well established in major disease networks)[5]

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