S-phase kinase associated protein 1 pseudogene 3 (SKP1P3)

SKP1P3 is a pseudogene of the S-phase kinase-associated protein 1 (SKP1) gene, meaning it is a non-coding genomic sequence homologous to SKP1 but does not produce a functional protein product. The canonical SKP1 protein is an essential adaptor subunit of the SCF (Skp1-Cullin-F-box) E3 ubiquitin ligase complex, which has a critical role in protein ubiquitination and cell cycle regulation[1][2]. However, SKP1P3 itself is not a protein-coding gene, does not produce a functional protein, and is not considered a therapeutic target, enzyme, receptor, or otherwise druggable target. There are currently no known biological functions, disease associations, or drugs interacting specifically with SKP1P3. The name may introduce confusion due to its similarity to the functional SKP1 gene and protein, which are extensively studied in oncology, cell cycle control, and targeted protein degradation, but SKP1P3 is not itself a proper drug target or functional molecule[1][2]. If your intention was to inquire about the actual functional molecule, refer to S-phase kinase-associated protein 1 (SKP1), not the pseudogene SKP1P3.

Other names

SKP1P3S-phase kinase-associated protein 1 pseudogene 3