S100 calcium binding protein A11 pseudogene (S100A11P)

This entry refers to a pseudogene of S100 calcium-binding protein A11, also known as S100A11. Pseudogenes are genomic DNA sequences similar to normal genes but are non-functional; they typically arise from gene duplication or retrotransposition and have lost the ability to encode a functional protein due to mutations. S100A11P (ENSG00000254924) does not produce a functional protein, is not implicated in human disease as a causative or diagnostic gene, and is not considered a therapeutic target. The functional protein S100A11 is a well-studied calcium sensor and regulator involved in cell growth, differentiation, apoptosis, and cancer, but this pseudogene should not be confused with the protein-coding S100A11 gene[3][6][7]. Key point: There is nothing therapeutically actionable or directly biologically relevant about this pseudogene in terms of drug targeting, biomarker use, or disease association. Most databases, when listing S100A11P, will reference it only as a pseudogene, sometimes with "see S100A11" for the functional counterpart. Extra clarification: If you are seeking information on the functional target, refer to S100 calcium binding protein A11 (S100A11) (not the pseudogene), which has recognized roles in cancer, inflammation, and cellular processes, and can interact with the RAGE receptor[1][7]. Summary of corrections: - This pseudogene should not be considered a protein target. - Entries referring to it as a therapeutic or diagnostic target are incorrect—mark as "is_incorrect: true." - For structural or functional information about the S100A11 protein, use the canonical S100A11 gene (ENSG00000163191), not ENSG00000254924.

Other names

S100A11PS100A11 pseudogeneS100A11P1S100A14