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Target intelligence / Profile preview
SALL1 antisense RNA 1 (SALL1-AS1)
- Target
- SALL1-AS1
- Molecular classification
- Long non-coding RNA (lncRNA), Antisense RNA, Other
01
Overview
SALL1 antisense RNA 1 (SALL1-AS1, also known as LOC105371256) is a long non-coding RNA classified as an antisense RNA, transcribed from the SALL1 gene locus, running in the opposite orientation to the SALL1 protein-coding transcript. Antisense lncRNAs often regulate their sense gene partners by recruiting chromatin-modifying complexes, influencing transcriptional activity, and modulating gene expression at the epigenetic level[2]. While many antisense lncRNAs are increasingly recognized for their ability to impact cancer progression and development in various tissues, no disease-specific role or direct associations with SALL1-AS1 have been established in current literature or databases. There are no known drugs targeting SALL1-AS1, and it is not currently considered a direct therapeutic target.
- Other names
- SALL1-AS1LOC105371256SALL1 antisense RNA 1
02
Biological functions
Regulation of gene expressionSpecifically acts in *cis* to regulate the neighboring SALL1 gene likely via epigenetic mechanisms[2]Potential involvement in chromatin modulation (inferred from general antisense lncRNA biology)[2]
03
Disease associations
Other (role in disease not directly established for SALL1-AS1 in available sources; antisense lncRNAs can play roles in cancer and development but no direct evidence for SALL1-AS1)
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