Salmonella enterica serovar Enteritidis (S. Enteritidis)

Salmonella enterica serovar Enteritidis is a Gram-negative, motile, facultatively anaerobic bacterium belonging to the family Enterobacteriaceae. It is one of the most common causes of foodborne illness globally, associated with outbreaks from contaminated poultry, eggs, and dairy products. The organism possesses multiple virulence factors, including the ability to form biofilms, survive harsh gastrointestinal conditions, and invade and persist in host tissues. It carries diverse antimicrobial resistance determinants—often located on plasmids—which contribute to its clinical significance by limiting effective treatment options. S. Enteritidis is characterized and subtyped through its flagellar H and somatic O antigens, and laboratory identification relies on serotyping, molecular detection of virulence genes, and antimicrobial susceptibility testing.

Other names

Salmonella EnteritidisS. EnteritidisSalmonella enterica subspecies enterica serovar Enteritidis

Antibiotic mechanisms targeting Salmonella Enteritidis primarily include: Inhibition of cell wall synthesis (e.g., beta-lactams like amoxicillin); Inhibition of protein synthesis (e.g., tetracyclines, aminoglycosides); Inhibition of DNA gyrase (e.g., quinolones); Inhibition of folate pathway (e.g., trimethoprim-sulfamethoxazole)