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Target intelligence / Profile preview
Salmonella enterica serovar Enteritidis O-antigen polysaccharide (O9)
- Molecular classification
- Polysaccharide, Lipopolysaccharide component, O-antigen
01
Overview
The O9 antigen polysaccharide is a key surface component of the lipopolysaccharide (LPS) layer in Salmonella enterica serovar Enteritidis, a major cause of foodborne illness worldwide. The O-antigen is responsible for the serological specificity of this bacterium and plays an important role in immune recognition, virulence, and vaccine development. It consists of repeating oligosaccharide units (mannose, rhamnose, galactose, and tyvelose) forming the outermost part of LPS. It provides protection against host defenses, contributes to bacterial virulence, and is a prime target for diagnostic assays and vaccine development against non-typhoidal Salmonella infections.
- Other names
- O9 antigenEnteritidis O-antigenSalmonella Enteritidis O9 polysaccharide
02
Biological functions
Immune evasionVirulence factorSurface componentSerological specificity
03
Disease associations
InfectionSalmonellosisFoodborne illness
04
Safety considerations
Potential for cross-reactivity with other Salmonella serovarsVariations in structure affecting vaccine efficacy
05
Biomarkers
O9 antigen presence for diagnosis
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