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Target intelligence / Profile preview
Salmonella enterica serovar Typhimurium (S. Typhimurium)
- Target
- S. Typhimurium
- Molecular classification
- Gram-negative bacterium, Enterobacteriaceae, Bacterium
01
Overview
Salmonella enterica serovar Typhimurium is a highly adaptable zoonotic pathogen responsible for significant global morbidity due to its robust environmental survival strategies and complex virulence mechanisms targeting both gastrointestinal colonization/infection and systemic dissemination when host defenses are compromised.
- Other names
- Salmonella typhimuriumNontyphoidal Salmonella (NTS)
02
Mechanism of action
Antibiotic action against bacterial targets (e.g., DNA gyrase, cell wall synthesis)
03
Biological functions
MotilityAdhesionInvasionImmune evasionBiofilm formationColonizationInfection
04
Disease associations
GastroenteritisSalmonellosisBacteremiaSepticemiaFoodborne illness
05
Safety considerations
Antibiotic resistanceMultidrug resistanceInvasive disease in immunocompromised individuals
06
Interacting drugs
Fluoroquinolones
2 more in the full profile.
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