Salmonella enterica subspecies enterica serovar Pullorum (S. Pullorum)

Salmonella enterica serovar Pullorum is a Gram-negative, non-motile bacterium that is highly host-adapted to poultry, serving as the causative agent of Pullorum disease [1]. The infection is characterized by high mortality in young chicks, often manifesting as 'bacillary white diarrhea,' while adult birds frequently become asymptomatic carriers [2]. This pathogen is primarily transmitted vertically from the reproductive tract of the hen to the embryo within the egg, making it a significant threat to the poultry industry [3]. While it is the focus of veterinary treatment, it is not a specific molecular target like a receptor or enzyme; instead, therapeutic strategies involve antibiotics that target internal bacterial components such as the cell wall or ribosomes [4]. Control measures in modern agriculture rely heavily on eradication programs and serological testing to identify and remove infected carriers from breeding flocks [5].

Other names

Salmonella pullorumBacterium pullorumBacillary white diarrhea bacteriumSalmonella enterica serovar Pullorum

As a whole organism, Salmonella pullorum is not a single molecular target; however, it is susceptible to various antibiotics that inhibit specific bacterial processes such as DNA gyrase activity (fluoroquinolones), cell wall synthesis (beta-lactams), and protein synthesis (tetracyclines and aminoglycosides) [1][2].