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Target intelligence / Profile preview
Salmonella Paratyphi A Antigen (Paratyphi A Antigen)
- Target
- Paratyphi A Antigen
- Molecular classification
- Lipopolysaccharide (LPS), O-antigen, Polysaccharide
01
Overview
Salmonella Paratyphi A antigen refers primarily to the O-antigen (specifically O:2) located on the lipopolysaccharide (LPS) layer of the bacterium Salmonella enterica serovar Paratyphi A. This antigen is a key virulence factor and a primary target for immune recognition, diagnostic assays, and vaccine development for paratyphoid fever. It elicits a strong antibody response and is crucial for bacterial survival and pathogenicity through its role in host-pathogen interactions and activation of the inflammatory response.
- Other names
- S. Paratyphi A O-antigenO:2 antigenGroup A O-antigenSalmonella Paratyphi A LPSParatyphi A GMMA
02
Biological functions
Bacterial cell structureImmune stimulationHost-pathogen interactionEndotoxin activityAdhesionComplement activation
03
Disease associations
Paratyphoid feverBacterial infectionSystemic infectionInflammation
04
Safety considerations
Endotoxic shockInflammatory responsePotential for cross-reactivity with other Salmonella serotypes (limited)Diagnostic inaccuracies
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