SARS-CoV-2 infected cells

"SARS-CoV-2 infected cells" is a collective term describing any cell that has been invaded by the SARS-CoV-2 virus, the causative agent of COVID-19. This phrase does not specify a single molecular entity or receptor but rather denotes the infection state of various cell types susceptible to viral entry and replication. SARS-CoV-2 infection leads to characteristic changes in host cells, involving expression of viral proteins, altered host gene expression, and disruptions in cellular and organelle function. The virus typically gains entry via angiotensin-converting enzyme 2 (ACE2) and may use other co-receptors. 'SARS-CoV-2 infected cells' is not a molecularly defined therapeutic target, but rather a descriptive category useful for clinical diagnostics, research studies, or therapeutic context when targeting infected rather than uninfected cells."[1][2][4][5][6]

Other names

Cells infected by SARS-CoV-2SARS-CoV-2 positive cellsCOVID-19 infected cellsCoronavirus-infected cellsSARS2-infected cells