Scaffold for tissue regeneration

Scaffolds for tissue regeneration are engineered biomaterials—often composed of natural or synthetic polymers, or decellularized extracellular matrix—designed to facilitate the growth and integration of new tissue in damaged or defective sites. Scaffolds replicate the essential biophysical and biochemical environment of the extracellular matrix, supporting cell adhesion, migration, and proliferation, and can enable the delivery of growth factors or cells. Key design requirements include high porosity for nutrient diffusion, appropriate mechanical strength to support tissue formation, bioactivity to stimulate cell differentiation, and controlled degradation to allow eventual replacement by native tissue. Scaffolds are central to tissue engineering strategies for regenerating muscle, bone, cartilage, nerves, and other tissues, but are not therapeutic targets in the classical pharmacological sense[1][2][3][4].

Other names

tissue engineering scaffoldbiomaterial scaffoldregenerative scaffoldtissue scaffold