Scavenger receptor family member expressed on T cells 1 (SCART1)

Scavenger receptor family member expressed on T cells 1 (SCART1) is a transmembrane protein encoded by the SCART1 gene, classified within the scavenger receptor cysteine-rich (SRCR) superfamily[1][2][3][5]. SCART1 is predicted to participate in immune responses, particularly within T cell-mediated pathways, potentially serving as a co-receptor on αβ and γδ T cells[1][2][5]. Expression is reported in lymph nodes, trachea, lung, and enriched in certain T cell populations[2][5]. The protein’s SRCR domains may facilitate pattern recognition, similar to other family members such as CD163 and WC1[2]. SCART1's role in human biology and disease remains under-characterized, and no therapeutic agents or validated clinical biomarkers are currently reported for this protein[1][2][5].

Other names

Scavenger receptor cysteine-rich domain-containing protein SCART1SCART1CD163c-alphaScavenger receptor family member expressed on T cells 1scavenger receptor cysteine-rich domain-containing protein SCART1scavenger receptor protein family member