Target intelligence / Profile preview

SDAD1 antisense RNA 1 (SDAD1-AS1)

Target
SDAD1-AS1
Molecular classification
Long non-coding RNA (lncRNA), Antisense RNA, Natural antisense transcript
01

Overview

SDAD1 antisense RNA 1 (SDAD1-AS1) is a long non-coding RNA (lncRNA) transcribed from the antisense strand of the SDAD1 protein-coding gene locus on human chromosome 4q21.1. As an antisense RNA, it is presumed to regulate the expression of its sense gene (SDAD1) through RNA-RNA interaction, potentially affecting SDAD1 mRNA stability or translation, or via epigenetic mechanisms. There is currently no evidence identifying SDAD1-AS1 as a therapeutic target, disease biomarker, or pharmacological receptor. It is part of the broad class of long non-coding, cis-acting, natural antisense transcripts that participate in gene regulation but do not code for proteins. No drug interactions, direct disease roles, or safety concerns have been reported for SDAD1-AS1.

Other names
SDAD1-AS1ENSG00000245928NCBI Gene 101928809HGNC:41106
02

Biological functions

Regulation of gene expression, likely in a cis-acting fashion by complementing the SDAD1 gene mRNA
03

Disease associations

Currently, no direct disease associations documented in primary sources for SDAD1-AS1; general lncRNA and antisense RNAs can have roles in cancer, cell proliferation, etc., but not yet specifically assigned to SDAD1-AS1

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