Target intelligence / Profile preview

Sebaceous Gland Cell

Molecular classification
Epithelial Cell, Exocrine Gland Cell
01

Overview

Sebaceous gland cells, or sebocytes, are specialized epithelial cells within sebaceous glands that synthesize and secrete sebum. Sebum is an oily substance that lubricates the skin and hair, provides a water barrier, and possesses antimicrobial properties. Sebocyte differentiation is regulated by androgens, and dysregulation can lead to skin disorders like acne.

Other names
Sebocyte
02

Biological functions

Sebum productionSkin lubricationHair lubricationWater barrierAntimicrobial defenseThermoregulation
03

Disease associations

Acne vulgarisSteatocystoma simplex/multiplexSebaceous hyperplasiaSebaceous adenomaSebaceous carcinoma
04

Biomarkers

KRT15TNCKRT75FSTFASD2EMAAndrogen Receptor

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