Sec1 family domain-containing protein 2 (SCFD2)

Sec1 family domain-containing protein 2 (SCFD2) is a protein involved in intracellular protein transport and vesicle-mediated trafficking processes, particularly in vesicle docking and fusion steps[1][3]. SCFD2 is predicted to interact with proteins involved in neurodevelopment and synaptic function, and is implicated in several biological processes across species, including cellular homeostasis and metabolism[2]. Elevated expression of SCFD2 is associated with a poorer prognosis in estrogen receptor-positive breast cancer, and functional studies indicate that SCFD2 supports tumor cell proliferation and endocrine therapy resistance, suggesting utility as a prognostic biomarker and a potential therapeutic target in cancer[1]. Furthermore, SCFD2 has emerging links to neurodevelopmental diseases, including autism and schizophrenia, where rare pathogenic alleles may contribute to susceptibility[2]. Its precise molecular function is still being elucidated, but its role in vesicle trafficking indicates involvement in fundamental cellular logistics[2][3].

Other names

STXBP1L1Syntaxin-binding protein 1-like 1FLJ39514sec1 family domain-containing protein 2syntaxin binding protein 1-like 1