Secreted frizzled-related protein 4 pseudogene

The secreted frizzled-related protein 4 pseudogene (ENSG00000284659) is a non-functional DNA sequence resembling the protein-coding gene for secreted frizzled-related protein 4 (SFRP4). Unlike the functional SFRP4 gene, this pseudogene does not produce any active protein or play a known direct role in cellular processes, disease mechanisms, or drug targeting. Pseudogenes are generally considered evolutionary remnants, though some can have subtle effects on gene regulation in specific contexts, usually via RNA transcripts, but no such function has been specifically reported for this SFRP4 pseudogene[2][4][6]. Key clarification: If the intent is to obtain therapeutic or biological information relevant for drug discovery, the correct target should be the protein-coding *Secreted frizzled-related protein 4* (*SFRP4*) gene (e.g., ENSG00000106483), not its pseudogene. The pseudogene is not a therapeutic target.

Other names

SFRP4 pseudogenesecreted frizzled-related protein 4-likeSFRP4P