Target intelligence / Profile preview

Secretion associated Ras-related GTPase 1A pseudogene 1 (SAR1AP1)

Target
SAR1AP1
Molecular classification
Other (pseudogene)
01

Overview

Secretion associated Ras-related GTPase 1A pseudogene 1 (SAR1AP1) is a human pseudogene that is related by sequence to the SAR1A gene, which encodes a small GTPase involved in COPII-mediated vesicle trafficking from the endoplasmic reticulum to the Golgi apparatus. Unlike its functional relative SAR1A, SAR1AP1 does not code for an active protein and is transcriptionally silent or non-functional. Pseudogenes like SAR1AP1 can theoretically play regulatory roles at the RNA level in rare cases, but there is no evidence SAR1AP1 performs such a function. It is not considered a therapeutic target, receptor, transporter, enzyme, or signaling molecule, and no drugs, biomarkers, or clinical associations have been reported for this pseudogene.

Other names
hsSARA-pSARAP1dJ88J8.3
02

Biological functions

Other (serves no protein-coding functional role; pseudogenes may have regulatory noncoding RNA roles, but there is no evidence for such function for SAR1AP1 specifically)
03

Disease associations

Other (no disease associations identified; not known to play a role in disease as a coding or regulatory gene)

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