Target intelligence / Profile preview

Secretoglobin family 1D member 4 (SCGB1D4)

Target
SCGB1D4
Molecular classification
Other, Secreted protein, Secretoglobin family
01

Overview

Secretoglobin family 1D member 4 (SCGB1D4) is a small, secreted protein belonging to the secretoglobin family, which comprises structurally related proteins involved in immune modulation and tissue maintenance in mammals[1][2][4]. SCGB1D4 is a protein-coding gene found throughout the human body, with highest expression in lymph node, tonsil, cultured lymphoblasts, and ovary, and is inducible by interferon-gamma (IFN-γ) in lymphoblasts[2][7]. While detailed function for SCGB1D4 is not fully established, it appears to participate in regulation of chemotactic cell migration and invasion, suggesting a potential immunological role[1][2][4]. Secretoglobins, as a family, have been implicated in modulation of inflammation, tissue repair, and possibly tumorigenesis, but specific therapeutic targeting or drug interactions have not been established for SCGB1D4. It is not classified as a receptor, enzyme, transporter, or transcription factor, but as a small, secreted regulatory protein[2][4]. There is no established role as a therapeutic target or an approved biomarker, and no record of drugs or mechanisms of action directly involving this protein in current literature[1][2][3][7].

Other names
IFN-gamma-inducible secretoglobinIFN-γ-inducible secretoglobinIISUNQ517/PRO812
02

Biological functions

Immune responseRegulation of chemotactic cell migration and invasion
03

Disease associations

Otherpossibly cancer biomarker (based on general secretoglobin function)unclear direct association except Donohue Syndrome

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