Target intelligence / Profile preview

Secretoglobin family 3A member 1 (SCGB3A1)

Target
SCGB3A1
Molecular classification
Cytokine-like protein, Secretoglobin family
01

Overview

Secretoglobin family 3A member 1 (SCGB3A1) is a small, secreted cytokine-like protein encoded by the SCGB3A1 gene in humans[2][4][5]. It is predicted to act as a cytokine, localized in the extracellular space, and is notably involved in the inhibition of cell growth and the positive regulation of myoblast fusion[1][4][5]. Diseases associated with SCGB3A1 include atrophy of the prostate and adenoid hypertrophy. The protein is also sometimes referred to as "High in normal-1" (HIN-1), indicating a potential role in tissue homeostasis and response to pathological states[1][5]. There is no direct evidence for specific drug interactions, biomarker roles, or safety concerns in the current literature.

Other names
HIN1PNSP2UGRP2UNQ629/PRO1245PnSP-2LU105Cytokine HIN-1High in normal 1Pneumo secretory protein 2Uteroglobin-related protein 2cytokine high in normal-1cytokine HIN-1
02

Biological functions

Cytokine activityNegative regulation of cell growthPositive regulation of myoblast fusion
03

Disease associations

Cancer (relevant in cell growth inhibition)Atrophy of prostateAdenoid hypertrophy

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